Method for activating helper T cells

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专利权人:

大塚製薬株式会社;株式会社癌免疫研究所

发明人:

杉山 治夫,十河 真司,佐藤 政芳,北本 竜生,後藤 義博

申请号：

JP2012537718

公开号：

JP6134139B2

申请日:

2011.10.04

申请国别(地区):

JP

年份:

2017

代理人:

摘要：

The present invention relates to a method for activating helper T cells, which includes the step of activating helper T cells by adding a WT1 peptide to antigen presenting cells, wherein the WT1 peptide has the ability to bind to any MHC class II molecule of an HLA-DRB1*0101 molecule, an HLA-DRB1*0401 molecule, an HLA-DRB1*0403 molecule, an HLA-DRB1*0406 molecule, an HLA-DRB1*0803 molecule, an HLA-DRB1*0901 molecule, an HLA-DRB1*1101 molecule, an HLA-DRB3*0202 molecule, an HLA-DRB4*0101 molecule, an HLA-DPB1*0201 molecule or an HLA-DPB1*0301 molecule, and the like.

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