BEHENNA, DOUGLAS CARL,毕汉纳 道格拉斯,畢漢納 道格拉斯,CHEN PING,陈 平,陳 平,FREEMAN-COOK, KEVIN DANIEL,富利门库克 凯文,富利門庫克 凱文,HOFFMAN, ROBERT LOUIS,霍夫曼 罗伯特,霍夫曼 羅伯特,JALAIE, MEHRAN,嘉莱 默赫兰,嘉萊 默赫蘭,NAGATA, ASAKO,永田麻子,NAIR,
申请号:
TW106126113
公开号:
TWI663169B
申请日:
2017.08.02
申请国别(地区):
TW
年份:
2019
代理人:
摘要:
This invention relates to compounds of general Formula (I) and pharmaceutically acceptable salts thereof, in which R1, R2, R2A, R2B, R3, R4, R5A, R5B, R6, R7, R8, R9, p, q and r are as defined herein, to pharmaceutical compositions comprising such compounds and salts, and to methods of using such compounds, salts and compositions for the treatment of abnormal cell growth, including cancer.本發明關於通式(I)化合物 及其醫藥上可接受之鹽類,其中R1、R2、R2A、R2B、R3、R4、R5A、R5B、R6、R7、R8、R9、p、q和r係如本文中所定義,關於包含此等化合物及鹽類之醫藥組成物,及關於使用此等化合物、鹽類及組成物治療異常的細胞生長(包括癌)之方法。