GALACTOSAMINOGALACTAN COMPRISING alpha-1-4 LINKED GALACTOSE AND alpha-1-4 LINKED N-ACETYLGALACTOSAMINE FOR USE IN THE TREATMENT OF AT LEAST ONE INFLAMMATORY DISEASE
Jean-Paul LATGE,Thierry Vincent Gérard FONTAINE,Frank Leo VAN DE VEERDONK,Mark Sebastiaan GRESNIGT,Mihai NETEA,Leo AB JOOSTEN,Luigina ROMANI,Silvia BOZZA,Antonella DE LUCA
申请号：
US14760604
公开号：
US20160008391A1
申请日:
2014.01.14
申请国别(地区):
US
年份:
2016
代理人:
摘要：
A first object of the invention is galactosaminogalactan comprising α1-4 linked galactose, α1-4 linked N-acetylgalactosamine, and optionally α1-4 linked galactosamine, for use in the treatment of at least one inflammatory disease. Another object of the invention is a pharmaceutical composition comprising a galactosaminogalactan comprising α1-4 linked galactose, α1-4 linked N-acetylgalactosamine, and optionally α1-4 linked galactosamine, as defined herein, and optionally a pharmaceutically acceptable carrier. Another object of the invention is a pharmaceutical composition according to the invention, for use in the treatment of at least one inflammatory disease. Another object of the invention is an inhibitor of IL-1RA for use in the treatment of human fungal diseases. Another object of the invention is a pharmaceutical composition comprising an inhibitor of IL-1RA, and optionally a pharmaceutically acceptable carrier.
