The present invention provides compositions and methods relating to or derivedfrom anti-PAR-2 antibodies. In particular embodiments, the invention providesantibodies that bind human PAR-2, PAR-2-binding fragments and derivatives ofsuch antibodies, and PAR-2-binding polypeptides comprising such fragments.Other embodiments provide nucleic acids encoding such antibodies, antibodyfragments and derivatives and polypeptides, cells comprising suchpolynucleotides, methods of making such antibodies, antibody fragments andderivatives and polypeptides, and methods of using such antibodies, antibodyfragments and derivatives and polypeptides, including methods of treating ordiagnosing subjects having PAR-2-related disorders or conditions.
