A lancet housing assembly (30; 400; 430; 452; 500; 600) comprising multiple lancets for use in a portable, hand-held medical diagnostic device (10) for sampling body fluids from a location in the skin of a patient, comprising the lancet housing assembly (30; 400; 430; 452; 500; 600): a carcass structure comprising multiple lancet compartments (40; 405; 444; 458; 505; 605), comprising at least one of the lancet compartments (40; 405; 444; 458; 505; 605): an outer facing side (64); one side facing inside (66); an opening (68; 446; 474; 544; 636) located on the outer facing side (64), is arranged and configured to align with a lancet opening (20) of the medical diagnostic device (10); and a lower surface (70, 84; 424) that extends between the outer facing side (64) and the inner facing side (66); a reactive material (72; 426; 436; 478; 532; 650) located on the bottom surface (70, 84; 424) and inside the lancet compartment (40; 405; 444; 458; 505; 605); and a lancet structure (24; 406; 432; 450; 506; 606) located in said at least one lancet compartment (40; 405; 444; 458; 505; 605), comprising the lancet structure (24; 406 ; 432; 450; 506; 606) one end (90; 408; 434; 462; 508; 608) of skin penetration and a part (92; 410; 464; 510; 610) of blood transport, adjacent to the end (90; 408; 434; 462; 508; 608) of skin penetration, in which the end (90; 408; 434; 462; 508; 608) of skin penetration, when extending through the opening (68; 446; 474; 544; 636), is shaped and sized to penetrate the patient's skin, in a place of the skin in order to provide a quantity of blood, the part being (92; 410; 464 ; 510; 610) of blood transport arranged and configured to receive the amount of blood from the end (90; 408; 434; 462; 508; 608) of penetration into the skin and to carry the amount of blood away from the place of the skin and even the reactive material (72; 426; 436; 478; 532; 650), wherein the lancet housing assembly further comprises one or more lancet guide rails (86, 88; 41