The present invention relates to the use of an undesirable medical condition associated with the presence and / or activity of urea-degrading bacteria in living organisms including humans, pets and farm animals, such as mammals, birds, amphibians, fish, mollusks or arthropods Wherein said undesirable medical condition is selected from the group consisting of the following bacteria in the gastrointestinal tract, respiratory system and / or genitourinary system: <； RTI ID = 0.0 >； Is a disease associated with the presence and / or activity of urea-degrading bacteria: urease-positive bacteria such as Helicobacter pylori , bacterial strains from the genus Brucella , Ureaplasma ureolyticum , other call alkali bacteria, such as Bacillus Pas toeri (Bacillus pasteurii), urease For generating reusi California Enterococcus coli car (Yersinia enterocolica) rod, a catheter and form a biofilm on the other medical devices, and urea-decomposing bacteria, infection of the oral mucosa which is involved and the precipitate the inorganic solidifying to, periodontal disease, causing dental caries urea-decomposing bacteria which are causing the formation of dental plaque, Proteus (Proteus), urea plasma (Ureaplasma), Klebsiella (Klebsiella), Pseudomonas (Pseudomonas), Stability Philo nose kusu (Staphylococcus), Providencia (Providencia), Genus Corynebacterium , especially blood. Urea-degrading bacteria that cause the formation of infectious stones in the process of urinary mechanical infection of P. mirabilis , and mycoplasma, mycoplasma, which is mycoplasma, hominis ) and oil. U. urealyticum . The invention also relates to the formation of colonies by urea-degrading bacteria which are harmful in living organisms including humans, pets and farm animals, such as mammals, birds, amphibians, fish, mollusks or arthropods, Dietary supplements, medicated food and food / feed additives containing alpha-ketoglutarate useful in preventing and inhibiting the formation of colonies of H. pylori
