In the present disclosure, a nanoliposomal formulation is achieved through a combination of the nature-friendly ingredients including hydrogenated lecithin and cholesterol, which are amphipathic materials, and caprylic/capric triglyceride. An ethanol-soluble, water-insoluble effective ingredient such as oleanolic acid is supported in the liposomes. In addition, the nanoliposomes prepared according to the present disclosure are stable and uniform in size.Dans la présente invention, une formulation nanoliposomale est obtenue par l'intermédiaire d'une combinaison d'ingrédients respectueux de la nature comprenant de la lécithine hydrogénée et du cholestérol, qui sont des matériaux amphipathiques, et des triglycérides capryliques/capriques. Un ingrédient efficace soluble dans l'éthanol et insoluble dans l'eau tel que l'acide oléanolique est supporté dans les liposomes. De plus, les nanoliposomes préparés selon la présente invention sont stables et de taille uniforme.본 개시에서는 자연 친화적인 성분으로 양친매성 물질인 수첨레시틴과 콜레스테롤, 카프릴릭/카프릭 트리글리세라이드의 조합을 통하여 나노리포솜 제형을 구현하고, 상기 리포솜에 올레아놀릭산과 같은 에탄올 용해성 수난용성 유효성분을 담지하였다. 또한 본 개시에 따라 제조된 나노리포좀은 안정하고 크기가 균일하다.
