This invention, the bacterial characteristic disease and the virus characteristic disease, mycosis, the inflammation or inflammation-related disease, painfully and deals with the composition and the method of remedying the condition of the skin. As for the particular composition, (a) it is constituted from the organic solvent extract which to mix with the water, (b) to mix to that methionine solution including the hypochlorite solution, manufactures the methionine (c) including the water non- miscibile organic solvent (d) with the method of including the step which separates organic solvent phase from water phase in order to obtain the organic solvent extract.本発明は、細菌性疾患、ウィルス性疾患、真菌症、炎症または炎症関連疾患、疼痛及び皮膚の症状を治療する組成物と方法を対象とする。当該組成物は、(a)メチオニンを水で混和し、(b)そのメチオニン溶液に次亜塩素酸塩溶液を加えて混和し、(c)水不混和性有機溶媒を加え(d)有機溶媒抽出液を得るために水相から有機溶媒相を分離するステップを含む方法により調製した有機溶媒抽出液から構成される。