DOW GLOBAL TECHNOLOGIES LLC;REGENTS OF THE UNIVERSITY OF MINNESOTA
发明人:
Ligeng Yin,Marc A. Hillmyer,Steven J. Guillaudeu,Robert L. Schmitt
申请号：
US14777838
公开号：
US20160289344A1
申请日:
2014.05.07
申请国别(地区):
US
年份:
2016
代理人:
摘要：
Esterified cellulose ethers comprising groups of formula —C(O)—CHR′—CHR″—COOA, wherein, R′ and R″ are hydrogen or (—S)m (—R1)n-R2, wherein R1 is a hydrocarbon group having 1 to 4 carbon atoms, R2 is an optionally substituted 5- or 6-membered cyclic group, m and n each independently are 0 or 1, and A is hydrogen or a cation, with the proviso that in each group CHR′—CHR″ one of R′ and R″ is hydrogen and the other one is (—S)m (—R1)n-R′, are useful as excipients for maintaining the concentration of poorly water-soluble drugs in aqueous liquids at supersaturation levels.
