A balloon catheter system and method for clearing blockage in the sinus ostium. The balloon catheter system and method employs a first balloon which dilates the sinus ostium while a second balloon removes an obstruction by resection. The system and method can then remove and/or drain any biological matter in the sinus. In some embodiments, the system employs an imaging device for viewing the anatomy and delivers irrigating and/or therapeutic agents to the sinus and/or sinus ostium.
