James M. Apgar,Ashok Arasappan,Tesfaye Biftu,Ping Chen,Danqing Feng,Erin Guidry,Jacqueline D. Hicks,Ahmet Kekec,Kenneth J. Leavitt,Bing Li,Troy McCracken,Iyassu Sebhat,Xiaoxia Qian,Lan Wei,Robert R. W
申请号:
US14419774
公开号:
US20150284411A1
申请日:
2013.08.19
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Novel compounds of the structural formula (I) are activators of AMP-protein kinase and may be useful in the treatment, prevention and suppression of diseases mediated by the AMPK activated protein kinase. The compounds of the present invention may be useful in the treatment of Type 2 diabetes, hyperglycemia, metabolic syndrome, obesity, hypercholesterolemia, and hypertension.