#$%^&*AU2012327190B220151224.pdf#####DECP-051/01US 313114-2291 ABSTRACT Compounds useful in the treatment of mammalian cancers and especially human cancers according to Formula I are disclosed. x1 N N N R3 H# X2 Y R2 Formula I Pharmaceutical compositions and methods of treatment employing the compounds disclosed herein are also disclosed. 109013 v4/BN