The present invention discloses a surgical guiding and positioning system, comprising: a global information device, a local information device, and a computing device. The global information device is capable of collecting an overall information of a surgical site before a surgical procedure begins. The local information device can comprise a surgical device including at least one sensor and provide a real-time information of a section of the surgical site. The computing device is capable of calculating a position data of the surgical device in the surgical site by comparing the overall information and the real-time information. Therefore, the present invention is capable of providing the real-time guidance and monitoring during a surgical procedure so that the surgeon can acquire precise real-time information of the surgical site and perform the surgery efficiently.
