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PHARMACEUTICAL COMPOSITION COMPRISING LINAGLIPTIN AND OPTIONALLY A SGLT2 INHIBITOR, AND USES THEREOF
专利权人:
BOEHRINGER INGELHEIM INTERNATIONAL GMBH
发明人:
EISENREICH, WOLFRAM
申请号:
NZ59402210
公开号:
NZ594022A
申请日:
2010.02.11
申请国别(地区):
NZ
年份:
2013
代理人:
摘要:
594022 Disclosed herein is a solid pharmaceutical dosage form comprising linagliptin as a first active ingredient in an amount of 5 mg, 1-chloro-4-(?-D-glucopyranos-1-yl)-2-[4-((S)-tetrahydrofuran-3-yloxy)-benzyl]-benzene as a second active ingredient in an amount from 5 mg to 25 mg, and one or more excipients; and the use of said dosage in the treatment of diabetes. Additionally, wherein the first active ingredient has a particle size distribution of X90<;200 µm, and the second active ingredient has a particle size distribution of 1 µm<;X90<;200 µm.
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