Glucagon analogs exhibiting physiological solubility and stability

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专利权人:

Richard D. Dimarchi;David L. Smiley

发明人:

Richard D. Dimarchi,David L. Smiley

申请号：

US12092802

公开号：

US08338368B2

申请日:

2006.11.06

申请国别(地区):

US

年份:

2012

代理人:

摘要：

Modified glucagon peptides are disclosed having improved solubility and stability, wherein the native glucagon peptide has been modified by pegylation, or the addition of a carboxy terminal peptide selected from the group consisting of SEQ ID NO: 19, SEQ ID NO: 20, SEQ ID NO: 21, or both.

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