An OCT tracking system includes an imaging unit operable to generate a fundus image of a patient's eye and a tracking system operable to process the fundus image to determine a location of a surgical instrument inserted into the patient's eye. The OCT tracking system further includes an OCT system including an OCT light source operable to generate an OCT imaging beam and a beam scanner. Based at least in part on the determined location of the surgical instrument, the beam scanner directs the OCT imaging beam to a particular region within the patient's eye, the particular region within the patient's eye including the determined location of the surgical instrument inserted into the patient's eye.