The present invention relates to: a ligand-binding molecule, the ligand-binding activity of which is reduced by the cleavage of a cleavage site； a production method for the ligand-binding molecule； a complex formed of the ligand-binding molecule and a ligand； a fusion protein including the ligand-binding molecule and a ligand； and a pharmaceutical composition including the ligand-binding molecule, or a fusion protein of the ligand-binding molecule and a ligand.
