Jay A. Berzofsky,Leon T. van den Broeke,Crystal L. Mackall,Lee J. Helman
申请号:
US14136124
公开号:
US09206245B2
申请日:
2013.12.20
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Disclosed are immunogenic peptides, related fusion proteins, nucleic acids encoding the peptides or fusion proteins, conjugates, expression vectors, host cells, and antibodies. Also, disclosed are pharmaceutical compositions, vaccines for use in the treatment or prevention of cancer, e.g., alveolar rhabodomyosarcoma, methods of stimulating a T cell to kill a tumor cell, methods of stimulating CD4+ and CD8+ T cells, and methods of treating or preventing cancer are further provided herein.