A retainer, system and method of tattoo removal including treating a tattooed region of skin with an oxidizing or bleaching solution activated by certain wavelengths of light may be provided. The method of tattoo removal may include applying a layer of removal solution to a tattooed region of skin regulating a temperature of the layer of removal solution with a temperature control element and exposing the layer of removal solution to a light source of pre-determined wavelength. Light of certain wavelengths may improve or “supercharge” the effects of certain pharmaceuticals or target chemicals and agents, creating a synergistic effect that may break down tattoo ink molecules and eliminate the appearance of tattoos in the skin of humans or other animals.