A method for placing a set of one or more markers in a luminal network in a patient's body, the method comprising using at least one hardware processor for: receiving image data of the anatomy of a luminal network of a patient and a location of at least one target in said luminal network anatomy； obtaining a rule set defining one or more rules for placing said set of one or more markers in said luminal network anatomy and with respect to said at least one target； during a survey performed by a user via a navigation system in a portion of the luminal network surrounding said at least one target, acquiring, via said navigation system, sample-locations in the surveyed portion of the luminal network； and identifying a set of one or more marker locations for placing said set of one or more markers from said acquired sample-locations, which complies with said rule set.
