CEMM - Forschungszentrum für Molekulare Medizin GmbH
发明人:
Robert Kralovics,Thorsten Klampfl,Heinz Gisslinger
申请号:
US16438575
公开号:
US20200040399A1
申请日:
2019.06.12
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention relates to a method for diagnosing myeloid malignancy comprising determining the presence of a mutant allele of the calreticulin gene. Also genomic sequences, cDNA sequences, mRNA sequences and protein sequences of the mutant calreticulin are subject of the present invention. Further, the invention relates to medical uses of inhibitors of mutant calreticulin.