Compounds derived from 3.5 - diamino - 2 - 6 - cloropirazin carboxamide, epithelial sodium channel blockers; Pharmaceutical composition, Methods to block sodium channels and to promote the Hydration of mucous Membranes; Treatment method; and use for Treatment of Asthma, bronchitis and Dry Skin, among others.
This invention provides chloro-pyrazine carboxamide derivatives useful as sodium channel blockers, compositions containing the same, therapeutic methods and uses for the same and processes for preparing the same.La solicitud se refiere a compuestos derivados de 3,5-diamino-6-cloropirazin-2-carboxamida, bloqueadores de los canales de sodio epiteliales, a su composición farmacéutica y a su uso para el tratamiento del asma, bronquitis y piel seca, entre otros.