INDUSTRY-ACADEMIC COOPERATION FOUNDATION; YEUNGNAM UNIVERSITY
发明人:
CHANG, HYEUN WOOK,장현욱,SON, JONG KEUN,손종근,HWANG, SEUNG LARK,황승락,JEONG, YONG TAE,정용태
申请号：
KR1020110142047
公开号：
KR1020130074152A
申请日:
2011.12.26
申请国别(地区):
KR
年份:
2013
代理人:
摘要：
PURPOSE: A composition containing citreorosein for preventing and treating metabolic syndrome is provided to ensure stable treatment effect without side effects and to be used as a pharmaceutical composition and a health food composition.CONSTITUTION: A composition for preventing or treating metabolic syndrome contains citreorosein. The metabolic syndrome is selected from the group consisting of hypertriglyceridemia, obesity, hypertension, arteriosclerosis, hyperlipidemia, liver diseases, hyperinsulinemia, hyperglycermia, diabetes, and insulin resistance disorder. The diabetes is type 2 diabetes. Citreorosein activates LKB1 (liver kinase B1) and increases glucose uptake in a cell by activated AMPK (AMP-activated protein kinase). A pharmaceutical composition for preventing or treating metabolic syndrome contains citreorosein. A health food composition for preventing or treating metabolic syndrome contains citreorosein.COPYRIGHT KIPO 2013본 발명은 대사증후군 예방 또는 치료용 조성물에 관한 것으로, 보다 구체적으로 시트레오로세인을 함유하는 고중성지방혈증, 비만, 고혈압, 동맥경화, 고지혈증, 간질환, 과인슐린혈증, 과혈당증, 당뇨병 및 인슐린 저항성질환으로 이루어진 군에서 선택된 하나 이상의 질환을 포함하는 대사증후군 예방 또는 치료용 조성물로서, 상기 조성물은 천연에서 분리된 화합물로 부작용이 적고 안정하며 대사증후군 치료 효과가 뛰어나기에 이를 약학 조성물 및 건강식품 조성물로 활용가능하다.
