Systems and methods allow for evaluating health conditions based on fingerprints and other skin patterns. A smartphone or other personal electronic device captures patient scans, such as fingerprint patterns transmitted from a wireless fingerprint scanner. Scans can be transmitted to a network-connected server for storage and analysis. The nature, frequency and location of patterns are compared to known correlations to generate a condition output. The condition output may then be made available to a patient and/or a medical professional, such as via notification message and/or access to a web portal.