The invention provides a PD-L1 antibody, an antigen-binding fragment thereof, and use of the antibody or antigen-binding fragment in the preparation of a medicament for treating PD-L1-mediated diseases or disorders.本發明提供了一種PD‑L1抗體,其抗原結合片段,以及該抗體或抗原結合片段在製備治療PD‑L1介導的疾病或病症的藥物中的用途。