THE BROAD INSTITUTE, INC.;PRESIDENT AND FELLOWS OF HARVARD COLLEGE;THE BRIGHAM AND WOMEN'S HOSPITAL, INC.;MASSACHUSETTS INSTITUTE OF TECHNOLOGY
发明人:
REGEV, AVIV,KUCHROO, VIJAY,PARK, HONGKUN,YOSEF, NIR,SHALEK, ALEXANDER K.,GAUBLOMME, JELLERT,JOLLER, NICOLE C.,WU, CHUAN,ANDERSON, ANA CARRIZOSA
申请号：
CA2902940
公开号：
CA2902940A1
申请日:
2014.02.27
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
This invention relates generally to compositions and methods for identifying the regulatory network that modulates, controls or otherwise influences T cell balance, for example, Thl7 cell differentiation, maintenance and/or function, as well compositions and methods for exploiting the regulatory network that modulates, controls or otherwise influences T cell balance in a variety of therapeutic and/or diagnostic indications. This invention also relates generally to identifying and exploiting target genes and/or target gene products that modulate, control or otherwise influence T cell balance in a variety of therapeutic and/or diagnostic indications.
