A tissue-sampling tool is made in the form of a tube presenting an inside face of circular section and an outside face of circular section, the tube having a blunt distal end and at least one sampling orifice extending symmetrically relative to a transverse plane and to a longitudinal plane. The orifice is peripherally bordered by two transverse borders that are symmetrical relative to the transverse plane and that are connected to two longitudinal borders that are symmetrical relative to the longitudinal plane. Each transverse border possesses a cutting edge situated at the intersection between said borders and the inside face, each transverse border co-operating with the inside face to form a cutting angle lying in the range 6° to 18°. The longitudinal borders have a cup-shape relative to the transverse borders, with a profile in the longitudinal plane that is different from the profile of the transverse borders.
