KWAK, HYUN HEE,LEE, GHUN IL,PARK, YONG MAN,SON, MI KYUNG,YANG, HI CHANG,KIM, TAE HYOUNG,KIM, YOON JI,KIM, BYONG MOON,LEE, SUNG HEE,KANG, SOO HYUNG,YOO, MOOHI
申请号：
EP08741460
公开号：
EP2139458A4
申请日:
2008.04.18
申请国别(地区):
EP
年份:
2013
代理人:
摘要：
Disclosed are biodegradable microspheres, capable of releasing a glucose-regulating peptide in a controlled manner, comprising a biodegradable polymer carrier with the glucose -regulating peptide encapsulated therein, and methods for the preparation thereof. In addition to ensuring high encapsulation efficiency and high stability of the encapsulated drug, the microspheres shows neither an initial burst effect nor incomplete release and allows the zero -order release of drugs over a prolonged period of time, thus improving the therapeutic effect of the drug.
