HICKIE ROBERT,BALSEVICH JOHN,RAMIREZ-EROSA IRVING,DUNLOP DONNA,BISHOP GREG,DEIBERT LEAH,ARNISON PAUL
申请号:
US20090934677
公开号:
US2011230430(A1)
申请日:
2009.03.26
申请国别(地区):
美国
年份:
2011
代理人:
摘要:
A saponin extract from Saponaria vaccaria and its use for stimulating apoptosis in cancer cells and treating cancer is described. The saponin extract may be isolated from Saponaria vaccaria seed. The saponin extract may comprise one or more than one triterpene saponin. The triterpene saponin may comprise a bisdesmosidic saponin having a molecular weight selected from the group consisting of molecular weight 1448, 1464, 1422, 1526, 1596 and 1688. Bisdesmosidic saponin of molecular weight 1448, 1464, 1422, 1526, 1596 and 1688 isolated from Saponaria vaccaria seed may be used to treat human cancer including prostate cancer, human breast cancer and colon cancer. Also disclosed is a method of isolating the saponin extract.