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METODO PARA TRATAR CANCERES DE MAMA POSITIVOS A RECEPTOR DE ANDROGENO (AR) CON MODULADOR DE RECEPTOR DE ANDROGENO SELECTIVO (SARMS).
专利权人:
GTX; INC.
发明人:
JAMES T. DALTON,MITCHELL S. STEINER,RAMESH NARAYANAN,SUNJOO AHN
申请号:
MX2015000572
公开号:
MX2015000572A
申请日:
2013.03.07
申请国别(地区):
MX
年份:
2015
代理人:
摘要:
This invention relates to the treatment of androgen receptor-positive breast cancer in a subject, for example a female subject. Accordingly, this invention provides methods of: a) treating a subject suffering from breast cancer; b) treating a subject suffering from metastatic breast cancer; c) treating a subject suffering from refractory breast cancer; d) treating a subject suffering from AR-positive breast cancer; e) treating a subject suffering from AR-positive refractory breast cancer; f) treating a subject suffering from AR-positive metastatic breast cancer; g) treating a subject suffering from AR-positive and ER-positive breast cancer; h) treating a subject suffering from triple negative breast cancer; i) treating a subject suffering from advanced breast cancer; j) treating a subject suffering from breast cancer that has failed SERM (tamoxifen, toremifene), aromatase inhibitor, trastuzumab (Herceptin, ado-trastuzumab emtansine), pertuzumab (Perjeta), lapatinib, exemestane (Aromasin), bevacizumab (Avastin), and/or fulvestrant treatments; k) treating, preventing, suppressing or inhibiting metastasis in a subject suffering from breast cancer; 1) prolonging survival of a subject with breast cancer, and/or m) prolonging the progression-free survival of a subject with breast cancer; comprising administering to the subject a therapeutically effective amount of a selective androgen receptor modulator (SARM) compound, comprising administering to the subject a therapeutically effective amount of a SARM compound of this invention.Esta invención se refiere al tratamiento del cáncer de mama positivo a receptor de andrógeno en un sujeto, por ejemplo una mujer. Por consiguiente, esta invención proporciona métodos para: a) tratar a un sujeto que padece cáncer de mama; b) tratar a un sujeto que padece cáncer de mama metastásico; c) tratar a un sujeto que padece cáncer de mama refractario; d) tratar a un sujeto que padece cáncer de mama positivo a AR; e) tratar a un sujeto que p
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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