BEN GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY
发明人:
COHEN, SMADAR,LEOR, JONATHAN
申请号：
CA2524356
公开号：
CA2524356C
申请日:
2004.05.04
申请国别(地区):
CA
年份:
2015
代理人:
摘要：
A composition for promoting repair of damaged tissues, being a cross-linkedalginate solution, which can be maintained in liquid form indefinitely (underconstant conditions) and only gels in vivo. This cross-linked alginatesolution is an ideal material to be used for tissue repair. Injection of saidmaterial into cardiac tissue post-myocardial infarct induced tissueregeneration. The invention provides such injectable solution, as well ascompositions and method of preparation thereof. The invention also providesvarious methods and uses of the cross-linked alginate solution, for cardiactissue regeneration, induction of neo-vascularization, enhancing SDF-1expression and guiding stem cell chemotaxis, among others. A kit for tissuerepair is also provided.
