JANSEN, Timothy,TOM, Samson,DANILKOVITCH, Alla,YOO, Dana,ZERHUSEN, Jaime,TODD, Gabriele Putz,JOHNSON, Amy Elizabeth
申请号:
EP14891336
公开号:
EP3139935A4
申请日:
2014.05.07
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
This invention provides a therapeutic placental composition comprising placental cells and other placental components derived from placental tissue. A cryopreserved placental composition is also provided. The placental compositions can be used to stimulate and promote angiogenesis, reduce inflammation, and to reduce scar formation, among others. The placental tissue can optionally be an amnion, chorion, a trophoblast-depleted chorion, umbilical cord, Whartons jelly, placental cotyledon, and/or maternal decidua. The placental composition of the present invention is useful in treating a patient with a tissue injury (e.g., wound or burn) by applying the placental composition to the injury or in close proximity. Placental compositions may also be used to promote or increase regeneration of tissue. Similar application is useful with ligament and tendon repair and for engraftment procedures such as bone engraftment.