Yasuyoshi Arikawa,Benjamin Jones,Betty Lam,Masashi Takahashi,Christopher Smith,Qing Dong,Victoria Feher,Zhe Nie
申请号：
US15681953
公开号：
US20180141951A1
申请日:
2017.08.21
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Disclosed are compounds of Formula 1,and pharmaceutically acceptable salts thereof, wherein G, L1, L2, R1, R2, R3, and R4 are defined in the specification. This disclosure also relates to materials and methods for preparing compounds of Formula 1, pharmaceutical compositions containing them, and their use for treating disorders, diseases, and conditions involving the immune system and inflammation, including rheumatoid arthritis, hematological malignancies, epithelial cancers (i.e., carcinomas), and other disorders, diseases, and conditions for which inhibition of SYK is indicated.
