Sean Brynjelsen,Mark Doty,James E. Kipp,Nailesh Jayswal,Krishnaswamy Narayanan
申请号：
US10920578
公开号：
US08722091B2
申请日:
2004.08.17
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention relates to a process for preparing submicron sized nanoparticles of a poorly water soluble compound by lyophilizing a dispersion or microdispersion of a multiphase system having an organic phase and an aqueous phase, the organic phase having the poorly water soluble organic compound therein. The method is preferably used to prepare nanoparticles of a poorly water soluble, pharmaceutically active compound suitable for in vivo delivery, particularly by parenteral routes.
