Yi Zhang,Scott A. Meyer,Jeffrey E. Stahmann,Carlos Alberto Ricci,Marina Brockway,Aaron R. McCabe,Yinghong Yu,Donald L. Hopper
申请号：
US12847657
公开号：
US08626276B2
申请日:
2010.07.30
申请国别(地区):
US
年份:
2014
代理人:
摘要：
Cardiac monitoring and/or stimulation methods and systems that provide one or more of monitoring, diagnosing, defibrillation, and pacing. Cardiac signal separation is employed to detect, monitor, track and/or trend ischemia using cardiac activation sequence information. Ischemia detection may involve sensing composite cardiac signals using implantable electrodes, and performing a signal separation that produces one or more cardiac activation signal vectors associated with one or more cardiac activation sequences. A change in the signal vector may be detected using subsequent separations. The change may be an elevation or depression of the ST segment of a cardiac cycle or other change indicative of myocardial ischemia, myocardial infarction, or other pathological change. The change may be used to predict, quantify, and/or qualify an event such as an arrhythmia, a myocardial infarction, or other pathologic change. Information associated with the vectors may be stored and used to track the vectors.
