The present invention provides a pharmaceutical composition for reducing local fat, wherein comprises a pharmaceutically acceptable aqueous solution, drug-containing micelles made of surfactants, and resveratrol encapsulated in said drug-containing micelles. This pharmaceutical composition for reducing local fat can reduce the fat at the administration site, and has the advantages of high stability, high fat tissue bioavailability, few side effects, and sustained release.本發明提供一種用於減少局部脂肪的醫藥組成物，包含醫藥上可接受之水溶液、界面活性劑所形成的複數個含藥微胞、以及被包覆在所述含藥微胞中的白藜蘆醇。所述用於減少局部脂肪的醫藥組成物可減少施用部位的脂肪，且具有高安定性、高度脂肪組織生體可用率、低副作用、以及緩釋等優點。
