The present invention relates to exogenous compositions and methods of theiruse, wherein the exogenous chemicalsare applied to one or more surface layers of plants to generate a herbicidalbiological response and in particular to a glyphosate-basedherbicidal composition for spray application to a plant having superiorproperties of herbicidal cuticle layer coating and penetration,herbicidal uptake, and herbicidal translocation, without cuticle layer damage.