Philip Mallinder;Keith Bowers;Steven Godfrey Lane;Isabelle Veronique Yolande Ossona De Mendez
发明人:
Keith Bowers,Steven Godfrey Lane,Philip Mallinder,Isabelle Veronique Yolande Ossona De Mendez
申请号：
US12516935
公开号：
US08153128B2
申请日:
2007.11.28
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Binding members, especially antibody molecules that bind the IL-6:IL-6Ra complex formed by IL-6 and IL-6Ra, and do not bind either IL-6 or IL-6Ra alone. The binding members may have greater specificity for inhibiting pathological effects of IL-6 rather than beneficial effects of IL-6, as compared with binding members that bind IL-6 or IL-6Ra outside the IL-6:IL-6Ra complex.
