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Benzimidazole compound
专利权人:
Eisai R & D Management Co Ltd
发明人:
Kawahara, Tetsuya,Miyazawa, Shuhei,Harada, Hitoshi,Fujisaki, Hideaki,Kubota, Atsuhiko,Nagakawa, Junichi,Watanabe, Nobuhisa,Shinoda, Masanobu,Iida, Daisuke,Terauchi, Hiroki,Ueda, Masato
申请号:
NO20075904
公开号:
NO339502B1
申请日:
2007.11.15
申请国别(地区):
NO
年份:
2016
代理人:
摘要:
An object of the present invention is to provide a novel chemical compound useful as a therapeutic or prophylactic agent for acid-related diseases, having an excellent inhibitory effect against gastric acid secretion, an excellent effect of maintaining the inhibitory effect against gastric acid secretion, thereby maintaining intragastric pH high for a long time, and having more safety and appropriate physicochemical stability. Provided is a compound represented by where R 1 and R 3 may be the same or different and each represent a hydrogen atom or a C1-C6 alkyl group; R 2 represents (5,5-dimethyl-1,3-dioxan-2-yl)methoxy group, 5,7-dioxaspiro[2.5]oct-6-ylmethoxy group, 1,5,9-trioxaspiro[5.5]undec-3-ylmethoxy group, or (2,2-dimethyl-1,3-dioxan-5-yl)methoxy group; R 4 , R 5 , R 6 and R 7 represent a hydrogen atom, halogen atom, C1-C6 alkyl group, C1-C6 haloalkyl group, C1-C6 alkoxy group or C1-C6 haloalkoxy group; and W 1 represents a single bond, methylene or ethylene group, a salt thereof or a solvate of these.
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