Aspects of the present disclosure provides a novel strain Vibrio sp. DIR21 (accession number MCC 0081) that exhibits quenching of quorum sensing mechanism of a pathogenic bacteria Vibrio harveyi in an aquaculture. Further, the isolated Vibrio strain exhibits improvement in the Feed Conversion Ratio (FCR) of crustaceans (shrimp in particular) by way of its protease activity. An aspect of the present disclosure relates to a method of quenching quorum sensing mechanism of a pathogenic bacteria Vibrio harveyi in an aquaculture, said method including addition of a strain Vibrio sp. DIR21 (accession number MCC 0081) or culture broth thereof in said aquaculture to effect quenching of quorum sensing mechanism of said pathogenic bacteria Vibrio harveyi. Another aspect of the present disclosure provides a probiotic composition including a strain Vibrio sp. DIR21 (accession number MCC 0081) or culture broth thereof, wherein said probiotic composition exhibits quenching of quorum sensing mechanism of Vibrio harveyi in an aquaculture.
