An instrument fixation device (10) includes a retaining ring (16), a ball joint (20) disposed within and movable relative to the retaining ring, and a locking mechanism (30). The ball joint defines a channel configured to receive an instrument therethrough. The locking mechanism includes a locking sleeve (32) and a lock (36). The locking sleeve is at least partially disposed within the retaining ring (16) and engages the outer surface of the ball joint. When the locking mechanism is in an unlocked position, the ball joint (20) is free to move within the retaining iing (16) and when the locking mechanism is in a first locked position, the locking sleeve engages the outer surface of the ball joint to fix the ball joint relative to the retaining ring.