Shifeng Liu;Mikhail A. Kondratenko;Serguei Svirid;Melwyn Abreo;Daniel F. Harvey;Rajender Kamboj;Heinz W. Gschwend;Chi Tu;Cindy J. Hudson;Vandna Raina;Wenbao Li;Vishnumurthy Kodumuru;Michael D. Winther
发明人:
Melwyn Abreo,Daniel F. Harvey,Heinz W. Gschwend,Wenbao Li,Chi Tu,Rajender Kamboj,Michael D. Winther,Vishnumurthy Kodumuru,Cindy J. Hudson,Mikhail A. Kondratenko,Shifeng Liu,Vandna Raina,Serguei Svirid
申请号:
US12552868
公开号:
US08153636B2
申请日:
2009.09.02
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Methods of treating an SCD-mediated disease or condition in a mammal, preferably a human, are disclosed, wherein the methods comprise administering to a mammal in need thereof a compound of formula (I):wherein x, y, W, V, R1, R2, R3, R4, R5, R6, R7, R7a, R8, R8a, R9, R9a, R10 and R10a are defined herein. Pharmaceutical compositions comprising the compounds of formula (I) are also disclosed.