An injectable composition comprising polymeric nanoparticles containing rapamycin with an improved water solubility and a method for preparing the same, and an anticancer composition comprising the same for a combination therapy with radiation
The present invention relates to a polymer nanoparticle injection formulation composition containing rapamycin with improved water solubility, and more specifically, to an injection formulation composition containing rapamycin wherein water solubility is improved by solubilizing rapamycin having low water solubility with polymer nanoparticles, a preparation method thereof, and an anticancer composition for a combined use with radiotherapy.본 발명은 향상된 수용해도를 갖는 라파마이신 함유 고분자 나노입자 주사제형 조성물, 보다 상세하게는 수용해도가 낮은 라파마이신을 고분자 나노입자로 가용화하여 수용해도를 향상시킨 라파마이신 함유 주사제형 조성물 및 그 제조방법, 및 방사선 요법과 병용하기 위한 항암 조성물에 관한 것이다.
