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ТРАНСДЕРМАЛЬНАЯ СИСТЕМА ДОСТАВКИ
专利权人:
ЛТС ЛОХМАНН ТЕРАПИ-СИСТЕМЕ АГ
发明人:
Хилле, Томас,Вауэр, Габриэль,Сайбертц, Франк,Вайнхаймер, Шу-Лун
申请号:
EA201592246
公开号:
EA201592246A1
申请日:
2014.06.04
申请国别(地区):
EA
年份:
2016
代理人:
摘要:
the present invention relates to \u0442\u0440\u0430\u043d\u0441\u0434\u0435\u0440\u043c\u0430\u043b\u044c\u043d\u043e\u0439 therapeutic system for \u0442\u0440\u0430\u043d\u0441\u0434\u0435\u0440\u043c\u0430\u043b\u044c\u043d\u043e\u0433\u043e of \u0431\u0443\u043f\u0440\u0435\u043d\u043e\u0440\u0444\u0438\u043d\u0430 comprising containing \u0431\u0443\u043f\u0440\u0435\u043d\u043e\u0440\u0444\u0438 mr. \u0441\u0430\u043c\u043e\u043a\u043b\u0435\u044f\u0449\u0443\u044e\u0441\u044f a layer like structure, containing a) an impenetrable to \u0431\u0443\u043f\u0440\u0435\u043d\u043e\u0440\u0444\u0438\u043d\u0430 protective layer and b) containing buprenorphine layer contact glue on the over, over \u043e\u043d\u0438\u0446\u0430\u0435\u043c\u043e\u043c for \u0431\u0443\u043f\u0440\u0435\u043d\u043e\u0440\u0444\u0438\u043d\u0430 protective layerthe glue layer contains (a) at least one contact adhesive based on a polymer, (b) an effective amount of \u0430\u043d\u0430\u043b\u044c\u0433\u0435\u0442\u0438\u0447\u0435\u0441\u043a\u0438 grounds \u0431\u0443\u043f\u0440\u0435\u043d\u043e\u0440\u0444\u0438\u043d\u0430 or fa \u0440\u043c\u0430\u0446\u0435\u0432\u0442\u0438\u0447\u0435\u0441\u043a\u0438 acceptable salt, (c) \u043f\u043e\u0432\u044b\u0448\u0430\u044e\u0449\u0435\u0435 viscosity substance involving a quantity of approximately 0.1% to 8% of the \u043a\u043e\u043d\u0442\u0430\u043a\u0442\u043d layer containing buprenorphine wow, clay, and (d) \u043a\u0430\u0440\u0431\u043e\u043d\u043e\u0432\u0443\u044e acid selected from the group.\u043e\u043b\u0435\u0438\u043d\u043e\u0432\u043e\u0439 \u043b\u0438\u043d\u043e\u043b\u0435\u0432\u043e\u0439 consisting of acid, acid, \u043b\u0438\u043d\u043e\u043b\u0435\u043d\u043e\u0432\u043e\u0439 acid, \u043b\u0435\u0432\u0443\u043b\u0438\u043d\u043e\u0432\u043e\u0439 acid and their mixtures in an amount sufficient to ensure that the \u0430\u043d\u0430\u043b\u044c \u0433\u0435\u0442\u0438\u0447\u0435\u0441\u043a\u0438 effective amount o
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