This present disclosure describes systems that use a constant current source to generate biphasic waveforms. In one example, a positive, constant current is generated from a single constant current source, and then applied to either end of an output workload in an alternating manner, such as at a predefined frequency. In another example, a constant current source is used to generate a positive phase, and a constant current sink along with a voltage source are used to generate a negative phase. An alternating adoption of these two phases, therefore, gives rise to the application of a biphasic waveform on an output workload.