Mayo Foundation for Medical Education and Research
发明人:
Keith L. Knutson,Andrea M. Henle
申请号：
US15810924
公开号：
US10117919B2
申请日:
2017.11.13
申请国别(地区):
US
年份:
2018
代理人:
摘要：
This document provides methods and materials for generating CD8− T cells having the ability to recognize cancer cells expressing a HER2/neu polypeptide. For example, methods and materials for using a polypeptide consisting of an SLAFLPESFD amino acid sequence in vivo or in vitro to generate CD8+ T cells having the ability to recognize and lyse cancer cells expressing a HER2/neu polypeptide are provided.
