A method for treating cancer in patients with creatinine clearance of 15 mL/min or more and less than 30 mL/min, including dividing a combination drug containing α,α,α-trifluorothymidine (FTD) and 5-chloro-6-[(2-iminopyrrolidine-1-yl)methyl]pyrimidine-2,4(1H,3H)-dione hydrochloride in a molar ratio of 1 : 0.5, in a dose of 30 to 50 mg/m2/day as FTD-equivalent, into two to four times a day, and orally administering it to the patient.本發明提供一種具有重度腎功能障礙之癌症患者之癌症治療方法。 本發明之治療方法係對肌酸酐清除率為15 mL/min以上未達30 mL/min之患者之癌症治療方法，其包括：對於以莫耳比1：0.5含有α,α,α-三氟胸苷(FTD)及5-氯-6-[(2-亞胺基吡咯啶-1-基)甲基]嘧啶-2,4(1H,3H)-二酮鹽酸鹽之複合劑，將以FTD換算量計為30~50 mg/m2/天之用量分為1天2~4次經口投予至上述患者。
