UNIVERSITY OF EXETER;QUEEN MARY UNIVERSITY OF LONDON;KING'S COLEGE LONDON
发明人:
Ahuva Nissim,David Perrett,Paul G. Winyard,Valerie M. Corrigall,Gabriel S. Panayi
申请号:
US14765863
公开号:
US20150377907A1
申请日:
2014.02.05
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention provides a method of diagnosing rheumatoid arthritis (RA), comprising: testing a sample from a subject for the presence or absence of antibodies against oxidised collagen II; wherein the presence of antibodies against oxidised collagen II in the sample is indicative of RA in the subject. The present invention also provides a method for identifying whether a subject responds to a disease modifying anti-rheumatic drug (DMARD) and related methods of treating RA, a method for identifying whether a subject responds to an anti-TNF biologic and related methods of treating RA, and a method of diagnosing osteoarthritis (OA).