FENG, YING,POST, LEONARD E.,SHEN, YUQIAO,RU, YUANBIN,WANG, EVELYN,YU, KAREN
申请号：
CA3003422
公开号：
CA3003422A1
申请日:
2016.10.26
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
Described are methods of treatment of a small cell lung cancer subject expressing Schlafen-11 (SLFN 11 ) with a Poly (ADP-ribose) polymerases (PARP) inhibitor or a pharmaceutically acceptable salt thereof. Specifically, the method comprising detecting SLFN 11 in a tumor cell sample from the subject, and administering effective amount of a PARP inhibitor, such as talazoparib or the tosylate salt of talazoparib, to the subject. :
