Guangyi Wang;David Bernard Smith;Jerome Deval;Leonid Beigelman;Natalia Dyatkina
发明人:
David Bernard Smith,Jerome Deval,Natalia Dyatkina,Leonid Beigelman,Guangyi Wang
申请号：
US13236435
公开号：
US08871737B2
申请日:
2011.09.19
申请国别(地区):
US
年份:
2014
代理人:
摘要：
Disclosed herein are phosphorothioate nucleotide analogs, such as thiophosphoroamidate prodrugs and thiophosphates (including α-thiomonophosphates, α-thiodiphosphates, and α-thiotriphosphates), methods of synthesizing phosphorothioate nucleotide analogs, such as thiophosphoramidate prodrugs, and thiophosphates and methods of treating viral infections, such as HCV, cancer, and/or parasitic diseases with the phosphorothioate nucleotide analogs, such as thiophosphoramidate prodrugs, and thiophosphates.
